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Dihydroquercetin-an important natural oxidant in the human body

2023 12/11

Dihydroquercetin, also known as DHQ, is a natural flavonoid found in querce (Quercus) and other plants. Querce is a common tree that is widely distributed around the world, including China, the United States, Europe and other places. Its endodermis is rich in dihydroquercetin. Research shows that dihydroquercetin has various biological activities such as antioxidant, anti-inflammatory, and anti-cancer.


Dihydroquercetin can be extracted and prepared through various methods, such as extraction from querce tree, chemical synthesis, etc. At present, dihydroquercetin has been widely used in medicines, health products, cosmetics and other fields.
Dihydroquercetin Taxifolin Jpg
In production, dihydroquercetin can be extracted from pine trees (Xinjiang larch, Tibetan longleaf pine, cedar, etc.). Extraction methods usually include solvent extraction, ultrasonic extraction, microwave-assisted extraction, etc. In addition, dihydroquercetin can also be prepared through chemical synthesis.

Dihydroquercetin has a variety of effects and effects. Here are some known research results:


Antioxidant effect: Dihydroquercetin has significant antioxidant activity and can neutralize free radicals, protect cells from oxidative stress damage, and slow down the aging process.
Anti-inflammatory effect: Dihydroquercetin has certain anti-inflammatory properties, can inhibit the production of inflammatory mediators, reduce inflammatory reactions, and has a certain alleviation effect on inflammation-related diseases.
Anti-cancer effect: Research has found that dihydroquercetin has an inhibitory effect on a variety of cancer cells. It can inhibit the proliferation of tumor cells, induce apoptosis, and block tumor metastasis and invasion.
Antibacterial effect: Dihydroquercetin shows certain inhibitory effects on a variety of bacteria, fungi and viruses, and has certain antibacterial and antiviral abilities.
Anti-thrombotic effect: Dihydroquercetin has been found to have anti-platelet aggregation effects, which can reduce the formation of thrombus and prevent thrombotic diseases.
In addition, dihydroquercetin has also been studied for anti-allergic reactions, protecting cardiovascular and cerebrovascular health, and improving skin conditions. However, these studies are still in the laboratory and animal stages, and further clinical studies are needed to verify its effects in humans. Efficacy and safety
Please note that the above content is only general information and does not constitute medical advice. If you need to use or take dihydroquercetin, please consult a professional doctor or pharmacist for advice.

Application fields of dihydroquercetin:
In the food industry, as a bioactive food additive, it can not only preserve food raw materials and the food itself, increase the shelf life, but also add preventive and therapeutic properties to the food.
In the industrial field, the performance of taxifol exceeds many known antioxidants in use, such as: anti-shock agent for engine fuels and rocket fuels; stabilizer for industrial lubricants.
In the agricultural field, it can be used to produce "plant growth regulators" to improve plant immunity and activity, enhance cold and drought tolerance, reduce maturity time, promote growth and increase yield.
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Physicochemical properties of dihydroquercetin:
Traits:Fine-grained crystals or amorphous powder, light yellow in color, no peculiar smell, and slightly bitter in taste.

solubility:Easily soluble in ethanol, acetic acid and boiling water, slightly soluble in cold water, almost insoluble in benzene.


melting point

240~242℃


In 2010, quercetin passed the FDA's GRAS certification and can be used in beverages, cereal products, pasta, processed fruits and juices, and gummies, with up to 500 mg of quercetin per serving. In Japan and Korea, quercetin is used as a food additive.

Currently, quercetin cannot be used in ordinary foods and health foods in my country. In 2021, China approved dihydroquercetin as a new food raw material, which can be used in beverages (≤20 mg/L), fermented milk and flavored fermented milk (≤20 mg/kg), cocoa products, chocolate and chocolate products (≤ 70 mg/kg). Dihydroquercetin is also a flavonol compound. Compared with quercetin, it has two more hydrogen atoms.


Dihydroquerpisol is a dihydroflavonol compound that belongs to the vitamin P family and is a widely used bioactive agent. Like other flavonoids, it has a variety of biological activities in the human body, including antioxidant , free radical scavenging, antiviral, anti-inflammatory, vasodilation and antibacterial effects. Dihydroquercetin is a new food antioxidant in the food industry. Its antioxidant capacity is comparable to many natural and synthetic antioxidants. It has not been found to have toxic reactions when used in large doses, and no experiments have found that it has teratogenic, allergic or mutagenic effects on the fetus.
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Dihydroquercetin has diverse physiological functions:
Douglas firin US FDA certification
Dihydroquercetin (Dihydroquercetin) was tested by the Forenhaar Biotechnology Research Center of Cook College of Rutgers University (The State University of New Jersey). This product has passed the US FDA certification to ensure that it is safe for the human body. Safe and effective.

Applications in the pharmaceutical industry: vitamin P, antiviral preparations, tumor prevention preparations, radiation protection preparations, capillary protection preparations, stomach and liver protection preparations and regulation of human immunity, and can improve blood flow and myocardium in patients with coronary heart disease Contractility, reducing cholesterol levels in the liver and blood, and quickly relieving human fatigue.


Application in cosmetics and hairdressing industry: In cosmetic products, it serves as an antioxidant and protective agent (can effectively extend the shelf life of products), and can promote the synthesis of collagen and elastin in the human body, eliminate acne, pimples, purulent rashes, and Can improve hair quality, whiten skin, activate skin elasticity
Application in facial creams and soaps: It can delay skin aging and restore youthful vitality to the skin.
Douglas fir, used as a conditioner and hair tonic, can promote hair growth and keep hair healthy.
In 1936, Hungarian scientists discovered an antioxidant substance that could improve the strength of capillaries and normalize the permeability of capillaries. Scientists classified it as a vitamin P family. Later, this substance was gradually extracted from yew, Douglas fir, larch and other plants, and was named "dihydroquercetin". Because Douglas fir is also called Douglas fir in North America, it is also called Douglas fir. Pinosin.

Since the 1960s, scientists have begun to conduct extensive research on the medicinal value of dihydroquercetin. The US CA database shows that 56 international authoritative institutions around the world are conducting scientific research.


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