Xi'an complex bio-tech CO.,LTD.

Xi'an complex bio-tech CO.,LTD.

What is Ectoine?What are his benefits?

2023 08/16

What is Ectoine?


Ectoine Powder also has another name, tetrahydromethylpyrimidine carboxylic acid, which is white powder and soluble in water. Is a cyclic amino acid that exists in salt-tolerant microorganisms that live in environments characterized by high UV radiation, dryness, extreme temperatures, and high salinity, and tetrahydromethylpyrimidinecarboxylic acid can survive in this environment The structure that protects proteins and cell membranes.

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As an osmotic pressure compensating solute, ectoine exists in salt-tolerant bacteria, and acts like a chemical transmitter in the cell. It has a stable protective effect on the cells in adverse environments, and can also stabilize the enzyme protein in the organism. Structure, has the function of revitalizing and anti-aging, can provide good moisturizing and sun protection functions, and has the effect of whitening the skin, and can also protect neutrophils, showing anti-inflammatory effects.


The earliest discovery of Ekdoin had to start with human "curiosity". In 1985, German scientist Professor Galinski discovered halophilic bacteria in the Wadi El Natrun salt lake in the Egyptian desert area. Halophilic bacteria will produce a natural protection ingredient (survival artist) Ectoin in the outer layer of cells under high temperature, dryness, strong UV radiation, and high salinity environment, thus starting the self-repair function!


Many high-salt lakes and saline-alkali lands, such as Chaka Salt Lake and Chaerhan Salt Lake in Qinghai, have found such "salt-tolerant" bacteria --- halophilic bacteria, which also produce ectoin excellent wild strains.

Unhealthy skin, on the surface it appears to be dry, sensitive, sagging, etc., but in fact there is something wrong with the cells, such as lack of water in the cells. The amount of water in the cell depends on the osmotic pressure. Osmotic pressure means that when the environmental salt content is high, the water in the cell will transfer to the environment; when the environmental salt content is low, the water will transfer from the environment to the cell, such as salt pickled vegetables. Osmotic pressure compensating solutes can protect the regulation of cells in different environments with high and low osmotic pressures, while not hindering the normal metabolic activities of cells. When the osmotic pressure is high, the free water in the cell will flow from the cell with high water potential to the outside of the cell with low water potential, resulting in dehydration of the cell.

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Halophilic bacteria are a kind of osmotic pressure compensating solute, which can discharge salt and adjust the concentration of osmotic pressure compensating solute in the cell, and can restore the water in the cell to normal. The mechanism is as follows:
(1) Salt excretion, some halophilic bacteria have the ability to absorb and concentrate K+ and discharge Na+ extracellularly, and use K+ to adjust osmotic pressure to achieve intracellular balance;
(2) Regulation of intracellular osmotic pressure compensation solute concentration. It can withstand the impact of osmotic pressure, and can repeatedly adjust the impact of osmotic pressure during the alternation of hypertonic and hypotonic environments. That is, hypotonic shock releases osmotic pressure compensating solutes, and hypertonic shock rapidly synthesizes osmotic pressure compensating solutes.
Scientists extract ectoine from the outer layer of cells of halophilic bacteria through fermentation and cultivation of halophilic bacteria, and use its special mechanism similar to that of halophilic bacteria to achieve the purpose of protecting and repairing the skin.

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The Functions of Ectoine Powder:
Ectoin, also known as "salt-tolerant bacteria extract", is a powerful Kosmotropic ordering substance. Its protection mechanism is very simple, but very effective. It can form a Protective case.
A number of clinical studies have confirmed that ectoine has the functions of protecting cells, nourishing, anti-aging and stabilizing.
Due to the existence of the protective shell, the skin cells are equivalent to being "armed", have a better "anti-strike ability", and are less likely to be stimulated by external stimuli, thereby reducing damage and inflammation.


1. Accelerate cell repair
When skin cells are under environmental stress, such as high temperature, ultraviolet radiation, hypoxia, heavy metal poisoning, virus infection, etc., ectoine will produce emergency protection and regeneration responses, and generate heat shock proteins to help each cell maintain normal physiological activities. According to Merck data, 1.0% ectoine can have a faster stress response, prevent cell damage, and increase the speed of self-healing and repair by 2 to 3 times.

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2. Repair UV damage
Ultraviolet rays can cause photoaging and accelerate skin aging. Ectoin prevents the chain reaction caused by UVA irradiation and prevents mt-DNA mutations induced by UVA. Ectoin can reduce the generation of second messengers induced by UVA in the cell membrane layer, reduce the activity of AP2 (activated transcription factor 2) in the protoplasm layer stimulated by UVA, and then reduce the pro-inflammatory factors in the nucleus such as ICAM-1 (intercellular adhesion molecule- 1). According to Merck data, 4.0% ectoine can reduce the formation of sunburned cells caused by ultraviolet radiation by 80% to 90%.

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3. Rescue the skin's ability to lock water
Under normal circumstances, adults lose about 240-480 ml of water per day through the skin surface. When the cuticle of the skin is severely damaged, the water loss can increase by 10 times. Ectoin can penetrate deep into the epidermis, which is different from the short-term and dependence of other moisturizers. It can truly repair the skin's water-locking system and make up for the phenomenon of rapid water loss after low-molecular hyaluronic acid injection. 1+1 > 2 .
According to Merck data, the experimental results: using products containing 0.5% and 1.0% ectoine, the skin moisturizing ability was improved in different proportions, and when ectoine was stopped for 7 days, the skin moisturizing ability was about 1.5 times that of the placebo group .

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4. Anti-aging and anti-wrinkle
For the "post-80s" and "post-90s" who regard anti-aging and anti-aging as their daily skin care routine, to evaluate whether a functional product is good or not, first look at whether it can improve crow's feet.
In this regard, Ekdoin's performance can be said to be very brilliant. Let's look at a group of "placebo-controlled" human experiments on crow's feet with a low concentration of 0.5% ectoine. (Inactive substance) A comparative experiment was carried out in which the product was applied around the eyes twice a day for 28 days.

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